Pharm

Chemotherapy-Induced Peripheral Neuropathy

search

Chemotherapy-Induced Peripheral Neuropathy

  • See Also
  1. Cancer Symptom
  2. Medication Causes of Neuropathy
  • Risk Factors
  1. Pre-existing Neuropathy (e.g. Diabetic Neuropathy)
  2. Chemotherapy
    1. Vinca alkyloids
    2. Taxanes
    3. Platinum Antineoplastic Compound
    4. Bortezomib
  • Presentations
  1. Acute
    1. Onset with drug infusion
  2. Chronic
    1. Onset within days to weeks, or even months, after Chemotherapy
  • Diagnostics
  1. History and exam is typically sufficient for diagnosis (EEG is not typically needed)
  • Management
  1. Exercise
  2. Acupuncture
  3. Medications
    1. Duloxetine
    2. Gabapentin and Pregabalin have been used (evidence lacking)
  • Prevention
  1. Exercise
  2. Compression therapy
  3. Cryotherapy
  4. Ganglioside-monosialic acid
  • References
  1. Eary (2026) Am Fam Physician 114(4): 393-411 [PubMed]